From $44,295 vs From $51,225


Choosing between the Honda Pilot and the Lexus Rx 350 is one of the most common decisions car buyers in the United States face. The Honda Pilot delivers 285hp @ 6100 while the Lexus Rx 350 produces 275hp @ 6000. On fuel, the Pilot returns 22 mpg est. while the Rx 350 uses 26 mpg est. — important in a market where fuel prices change monthly. Pricing starts at $44,295 for the Pilot and $51,225 for the Rx 350. Both vehicles have their merits. The right choice depends on your priorities: fuel economy, performance, towing ability, safety features or total cost of ownership. This comparison covers every specification available so you can make an informed decision.