From $42,795 vs From $49,245


Choosing between the Honda Odyssey and the Toyota Sienna is one of the most common decisions car buyers in the United States face. The Honda Odyssey delivers 280hp @ 6000 while the Toyota Sienna produces 245hp @ 6000. On fuel, the Odyssey returns 24 mpg est. while the Sienna uses 36 mpg est. — important in a market where fuel prices change monthly. Pricing starts at $42,795 for the Odyssey and $49,245 for the Sienna. Both vehicles have their merits. The right choice depends on your priorities: fuel economy, performance, towing ability, safety features or total cost of ownership. This comparison covers every specification available so you can make an informed decision.