VS
At a Glance
Power
591hp @ 6000
375hp @ 5500
Torque
590lb-ft @ 2050
369lb-ft @ 1600
Fuel
18 mpg est.
26 mpg est.
Engine
4.0 L/244ci
3.0 L/183ci
Choosing between the Audi A6 and the Mercedes-Benz E-Class is one of the most common decisions car buyers in the United States face. The Audi A6 delivers 591hp @ 6000 while the Mercedes-Benz E-Class produces 375hp @ 5500. On fuel, the A6 returns 18 mpg est. while the E-Class uses 26 mpg est. — important in a market where fuel prices change monthly. Pricing starts at $109,000 for the A6 and $63,900 for the E-Class. Both vehicles have their merits. The right choice depends on your priorities: fuel economy, performance, towing ability, safety features or total cost of ownership. This comparison covers every specification available so you can make an informed decision.
Specification
Audi A64.0 TFSI quattro 2021 - From $109,000
Mercedes-Benz E-ClassE 450 4MATIC Sedan 2026 - From $63,900
Performance
Power Output (hp)
591hp @ 6000
375hp @ 5500
Torque (lb-ft)
590lb-ft @ 2050
369lb-ft @ 1600
Engine & Drivetrain
Engine Capacity
4.0 L/244ci
3.0 L/183ci
Engine Layout
—
Inline
Cylinders
8
6
Fuel Type
Hybrid
—
Forced Induction Device
Turbocharged
Turbocharged
Transmission
Automatic
Automatic
Number of Gears
8
—
Drive Wheels
All Wheel Drive
All Wheel Drive
Fuel Economy
Fuel Economy (Combined, est.)
18 mpg est.
26 mpg est.
Fuel Economy - City (mpg)
15mpg
22mpg
Fuel Economy - Highway (mpg)
22mpg
31mpg
Fuel Tank Capacity (gal)
19.3gal
17.4gal
Dimensions
Length (in)
196.7in
194.9in
Width (in)
76.8in
73.7in
Height (in)
58.6in
57.9in
Wheelbase (in)
115.3in
116.6in
Curb Weight (lbs)
4960lbs
4376lbs
Safety
ABS
✓ Standard
✓ Standard
Brake Assist
✓ Standard
✓ Standard
Stability Control
✓ Standard
✓ Standard
Traction Control
✓ Standard
✓ Standard
Driver Airbag
✓ Standard
✓ Standard
Passenger Airbag
✓ Standard
✓ Standard
Side Airbags Front
✓ Standard
✓ Standard
Curtain Airbags
✓ Standard
✓ Standard
Features & Tech
Air Conditioning
✓ Standard
✓ Standard
Climate Control
✓ Standard
✓ Standard
Cruise Control
✓ Standard
✓ Standard
Adaptive Cruise Control
✓ Standard
✓ Standard
Bluetooth
✓ Standard
✓ Standard
Backup Camera
✓ Standard
✓ Standard
Rear Parking Aid
—
✓ Standard
Sunroof
✓ Standard
✓ Standard
Heated Seats
✓ Standard
✓ Standard
Power Seat Adjustment
✓ Standard
✓ Standard
Keyless Entry
✓ Standard
✓ Standard
Alloy Wheels
✓ Standard
✓ Standard
The Verdict
Which Wins?
Overall Winner
Mercedes-Benz E-Class
2 / 4 categories
Performance
A6
Fuel Economy
E-Class
Value
E-Class
Practicality
Tied
Pros & Cons
Audi A6
Well-rounded specification
Higher fuel consumption (18 mpg est.)
Higher starting price
Mercedes-Benz E-Class
Better fuel economy (26 mpg est.)
Lower starting price ($63,900)
Few notable weaknesses
Frequently Asked Questions
Which is more fuel efficient, the A6 or E-Class?
The A6 gets 18 mpg est. and the E-Class gets 26 mpg est. on the combined cycle. The E-Class is the more fuel-efficient choice. In real-world conditions with a mix of highway and urban driving, actual figures will be slightly higher.
Which has more power, the A6 or E-Class?
The A6 produces 591hp @ 6000 and 590lb-ft @ 2050 of torque while the E-Class delivers 375hp @ 5500 and 369lb-ft @ 1600 of torque. The A6 is the more powerful option.
What is the price difference between the A6 and E-Class?
The A6 starts from $109,000 and the E-Class from $63,900. The E-Class is cheaper by $45,100 at this variant level. Final on-the-road pricing varies by dealer and specification.
Should I buy the A6 or the E-Class?
It depends on your priorities. If fuel economy matters most, check the mpg figures above. If you need towing capacity, compare the towing ratings. For day-to-day driving - commutes, school runs and highway trips - consider ground clearance, service network coverage, and total cost of ownership including insurance and maintenance. Use the spec tables above to compare every detail before making your decision.